Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALPL | P05186 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454328 | 0.85 | GABRA1 (0.38) | KDM4EGAAGLALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL20268115 | 0.77 | PIN1 (0.43) | KDM4E | |
| SCHEMBL6299296 | 0.75 | GAA (0.46) | KDM4EGAAGLASPRMMP2 | |
| SCHEMBL70624 | 0.75 | GAA (0.67) | KDM4EGAAGLAMMP2MAPT | |
| SCHEMBL18093528 | 0.75 | SPR (0.54) | KDM4ESPRMMP2MAPTRAB9A | |
| SCHEMBL18093511 | 0.73 | P4HA1 (0.51) | KDM4EGAASPRMMP2MAPT | |
| SCHEMBL29621805 | 0.71 | KDM4E (0.45) | KDM4EGAAGLAMMP2MAPT | |
| SCHEMBL29621802 | 0.71 | KDM4E (0.45) | KDM4EGAAGLAMMP2MAPT | |
| SCHEMBL13804463 | 0.69 | GAA (0.58) | KDM4EGAAGLAMMP2MAPT | |
| SCHEMBL1422945 | 0.69 | KDM4E (0.58) | KDM4EGAAGLAMMP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023169436-A1 | BENZO BICYCLIC COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 广州市联瑞制药有限公司 | 2023-09-14 | — | — | WO | disclosed |