Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 12/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25405409 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL28601405 | 0.78 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| Hydrochloric Acid SCHEMBL20268115 | 0.76 | PIN1 (0.43) | KDM4E | |
| SCHEMBL19878642 | 0.70 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL12065780 | 0.66 | KIT (0.37) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL7165649 | 0.66 | HCAR2 (0.52) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL12867867 | 0.65 | ALOX15 (0.48) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL5838109 | 0.64 | ALDH1A1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL645520 | 0.63 | RAB9A (0.56) | GAA | |
| SCHEMBL1871973 | 0.62 | HSD17B10 (0.53) | KDM4EL3MBTL1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |