Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258510 | 0.85 | NPC1 (0.47) | ASIC3NPC1NISCHCA12CA1 | |
| SCHEMBL6308292 | 0.79 | PNMT (0.44) | ASIC3DRD2DRD3PNMTCD44 | |
| SCHEMBL6313377 | 0.79 | PNMT (0.44) | ASIC3DRD2DRD3PNMTCD44 | |
| SCHEMBL30481091 | 0.79 | PNMT (0.44) | ASIC3DRD2DRD3PNMTCD44 | |
| SCHEMBL5850255 | 0.76 | NPC1 (0.79) | NPC1NISCHCA12CA1CA2 | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL3328852 | 0.74 | PNMT (0.66) | ASIC3CA1CA2PNMTCD44 | |
| SCHEMBL6347388 | 0.74 | ASIC3 (0.65) | ASIC3DRD2DRD3CD274PNMT | |
| SCHEMBL25405046 | 0.73 | ASIC3 (0.59) | ASIC3DRD2DRD3CD274PNMT | |
| SCHEMBL8323150 | 0.72 | ASIC3 (0.78) | ASIC3DRD2DRD3CD274PNMT | |
| SCHEMBL28274279 | 0.72 | ASIC3 (0.63) | ASIC3DRD2DRD3CD274PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023174383-A1 | DIHYDROISOQUINOLINE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-09-21 | — | — | WO | disclosed |