Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254436 | 0.89 | GSK3A (0.41) | GSK3AGSK3BKMT2APGRLMNA | |
| SCHEMBL14877423 | 0.81 | GSK3A (0.44) | GSK3AGSK3BKMT2APGRTSHR | |
| SCHEMBL253247 | 0.70 | KDM4E (0.41) | KMT2AKDM4EALDH1A1MAPK1HIF1A | |
| SCHEMBL248654 | 0.69 | GSK3A (0.47) | GSK3AGSK3BKMT2APGRLMNA | |
| SCHEMBL15262057 | 0.69 | TP53 (0.57) | KMT2ALMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL31221623 | 0.66 | ALDH1A1 (0.44) | PGRKDM4EALDH1A1MAPK1 | |
| SCHEMBL252007 | 0.65 | LMNA (0.48) | GSK3AGSK3BKMT2APGRLMNA | |
| SCHEMBL15262211 | 0.64 | MAPK1 (0.41) | KMT2ALMNACA1CA2KDM4E | |
| SCHEMBL29626153 | 0.63 | KDM4E (0.48) | GSK3AGSK3BKMT2APGRLMNA | |
| SCHEMBL15261836 | 0.63 | EEF2K (0.53) | KMT2APGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542538-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |