Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254120 | 0.89 | GSK3A (0.39) | GSK3AGSK3BMAPK1CYP2C9TSHR | |
| SCHEMBL248654 | 0.80 | GSK3A (0.47) | GSK3AGSK3BMAPK1CYP2C9TSHR | |
| SCHEMBL253247 | 0.80 | KDM4E (0.41) | MAPK1ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL19377596 | 0.75 | ALDH1A1 (0.46) | GSK3AGSK3BMAPK1CYP2C9TSHR | |
| SCHEMBL252007 | 0.75 | LMNA (0.48) | GSK3AGSK3BMAPK1CYP2C9TSHR | |
| SCHEMBL15557582 | 0.70 | HTR3A (0.54) | CYP2C9TSHR | |
| SCHEMBL14877423 | 0.69 | GSK3A (0.44) | GSK3AGSK3BMAPK1TSHRALDH1A1 | |
| SCHEMBL14966907 | 0.68 | KMT2A (0.49) | GSK3AGSK3BKDM4EKMT2ALMNA | |
| SCHEMBL14877428 | 0.68 | TP53 (0.44) | GSK3AGSK3BALDH1A1KDM4EKMT2A | |
| SCHEMBL15262543 | 0.67 | TP53 (0.72) | MAPK1ALDH1A1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542538-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |