Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520324 | 1.00 | RAB9A (0.51) | RAB9ACYP1A2CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL30520309 | 0.76 | KDM4E (0.59) | RAB9ACYP2D6LTA4HKDM4EHTR2C | |
| SCHEMBL3254598 | 0.76 | KDM4E (0.59) | RAB9ACYP2D6LTA4HKDM4EHTR2C | |
| SCHEMBL19198136 | 0.76 | KMT2A (0.54) | RAB9ACYP1A2CYP3A4CYP2D6LTA4H | |
| SCHEMBL11060955 | 0.76 | LTA4H (0.51) | RAB9ALTA4HKDM4EHTR2CGSK3B | |
| SCHEMBL22236175 | 0.76 | ALDH1A1 (0.43) | HSD17B10TDP1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL19198153 | 0.74 | ALDH1A1 (0.64) | RAB9ALTA4HKDM4EHTR2CGSK3B | |
| SCHEMBL19197793 | 0.74 | KDM4C (0.61) | RAB9ACYP1A2CYP3A4CYP2D6LTA4H | |
| SCHEMBL3210499 | 0.72 | CHRNA7 (0.51) | RAB9ALTA4HCHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL13926774 | 0.72 | KDM4E (0.62) | RAB9ATDP1LTA4HKDM4EHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM5A, KDM1A | RAB9A 3032/4885CYP1A2 1445/4885CYP3A4 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.