Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108966 | 0.74 | PDE2A (0.49) | PDE2AKDM4EALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2357430 | 0.73 | KDM4E (0.61) | PDE2AKDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL30498955 | 0.72 | KDM4E (0.47) | PDE2AKDM4EALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2023340 | 0.71 | KDM4E (0.45) | CYP11B1CYP11B2PDE2AKDM4EALDH1A1 | |
| SCHEMBL2021844 | 0.71 | ALDH1A1 (0.43) | CYP11B1CYP11B2PDE2AKDM4EALDH1A1 | |
| SCHEMBL29972563 | 0.71 | GAA (0.51) | PDE2AKDM4EALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL23832439 | 0.67 | DRD1 (0.37) | CYP11B1CYP11B2ALDH1A1SIGMAR1MAPT | |
| SCHEMBL8081400 | 0.66 | CYP11B2 (1.00) | CYP11B1CYP11B2ALDH1A1CYP3A4CYP17A1 | |
| SCHEMBL28663639 | 0.65 | CYP11B1 (0.61) | CYP11B1CYP11B2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL23641045 | 0.65 | CYP11B2 (0.62) | CYP11B1CYP11B2ALDH1A1SIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | UNIV TEXAS (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | CREB1, RAPGEF4, ATF4 | CYP11B1 2539/4885CYP11B2 2715/4885PDE2A 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.