Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | CCR9 | P51686 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426301 | 0.90 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208475 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL25425543 | 0.81 | TSHR (0.49) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL6085414 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL14852224 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208411 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL1695664 | 0.76 | LOXL2 (0.57) | TSHRHTTKLKB1KLK1EPHX2 | |
| SCHEMBL14632407 | 0.75 | ALDH1A1 (0.65) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL24071313 | 0.75 | HDAC8 (0.57) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL18002722 | 0.75 | L3MBTL1 (0.45) | ALDH1A1KDM4ETSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204808-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | Promega Corporation (US) | 2023-07-05 | — | — | EP | disclosed |