Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208453 | 0.89 | PLK1 (0.38) | MTNR1AMTNR1BMCL1HDAC8MAPT | |
| SCHEMBL25423878 | 0.86 | KDM4E (0.41) | MTNR1AMTNR1BMCL1HDAC8HDAC6 | |
| SCHEMBL25426273 | 0.84 | MTNR1A (0.34) | MTNR1AMTNR1BMCL1HDAC8HDAC6 | |
| SCHEMBL29208419 | 0.80 | KDM4E (0.38) | MTNR1AMTNR1BMCL1HDAC8HDAC6 | |
| SCHEMBL29208414 | 0.76 | CCNC (0.38) | MTNR1AMTNR1BMCL1MAPT | |
| SCHEMBL29208443 | 0.74 | CA1 (0.37) | MTNR1AMTNR1B | |
| SCHEMBL25424001 | 0.72 | HDAC8 (0.35) | MTNR1AMTNR1BHDAC8HDAC6HDAC1 | |
| SCHEMBL25424948 | 0.71 | ALDH1A1 (0.40) | MTNR1AMTNR1BMCL1HDAC8HDAC6 | |
| SCHEMBL25426067 | 0.69 | CPB2 (0.36) | MTNR1AMTNR1BHDAC8HDAC6HDAC1 | |
| SCHEMBL25426712 | 0.67 | ALDH1A1 (0.45) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204808-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | Promega Corporation (US) | 2023-07-05 | — | — | EP | disclosed |