Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973972 | 0.86 | TRPV1 (0.39) | RAB9APDE10ATRPV1 | |
| SCHEMBL25377702 | 0.84 | RAB9A (0.42) | LMNAHPGDHTTRAB9ASMN1; SMN2 | |
| SCHEMBL25974745 | 0.81 | KIF11 (0.51) | HPGDRAB9ASMN1; SMN2PDE10A | |
| SCHEMBL25375690 | 0.79 | SMN1; SMN2 (0.41) | LMNAHPGDHTTRAB9ASMN1; SMN2 | |
| SCHEMBL25341793 | 0.79 | TRPV1 (0.47) | RAB9ASMN1; SMN2SCN9ATRPV1 | |
| SCHEMBL30519393 | 0.79 | TRPV1 (0.47) | RAB9ASMN1; SMN2SCN9ATRPV1 | |
| SCHEMBL25378460 | 0.78 | GRM4 (0.45) | LMNAHPGDHTTSMN1; SMN2PDE10A | |
| SCHEMBL25973903 | 0.78 | NPC1 (0.39) | RAB9ATRPV1 | |
| SCHEMBL25376091 | 0.78 | HTT (0.42) | LMNAHPGDHTTRAB9ASMN1; SMN2 | |
| SCHEMBL25974048 | 0.77 | TRPV1 (0.37) | HTTRAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |