Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409135 | 0.77 | CRBN (0.44) | SLC11A2TDP1ALDH1A1KDM4EGAA | |
| SCHEMBL8115803 | 0.68 | SLC11A2 (0.48) | SMN1; SMN2SLC11A2TDP1ALDH1A1KDM4E | |
| SCHEMBL29150182 | 0.66 | TDP1 (0.53) | SMN1; SMN2SLC11A2TDP1ALDH1A1KDM4E | |
| SCHEMBL565271 | 0.66 | SMN1; SMN2 (0.53) | SMN1; SMN2SLC11A2TDP1ALDH1A1KDM4E | |
| SCHEMBL5579491 | 0.64 | LMNA (0.53) | SMN1; SMN2SLC11A2TDP1ALDH1A1KDM4E | |
| SCHEMBL1267187 | 0.62 | ALKBH5 (0.47) | SLC11A2AKR1C3KDM4C | |
| SCHEMBL20991749 | 0.62 | HRH3 (0.45) | SMN1; SMN2 | |
| SCHEMBL409136 | 0.62 | TDP1 (0.38) | SLC11A2TDP1ALDH1A1KDM4EGAA | |
| SCHEMBL16794591 | 0.62 | LMNA (0.54) | SMN1; SMN2SLC11A2TDP1ALDH1A1KDM4E | |
| SCHEMBL1245039 | 0.62 | LMNA (0.46) | SLC11A2TDP1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |