Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25430620 | 0.77 | SMN1; SMN2 (0.43) | LMNAGLATDP1ALDH1A1GAA | |
| SCHEMBL7830035 | 0.71 | CRBN (0.55) | CRBNDDB1L3MBTL1RXFP1 | |
| SCHEMBL5579491 | 0.70 | LMNA (0.53) | LMNAGLATDP1ALDH1A1GAA | |
| SCHEMBL5820389 | 0.70 | LMNA (0.42) | LMNAGLATDP1ALDH1A1GAA | |
| SCHEMBL28392243 | 0.70 | CRBN (0.42) | CRBNDDB1LMNAALDH1A1GAA | |
| SCHEMBL28939023 | 0.70 | LMNA (0.42) | LMNAGLATDP1ALDH1A1GAA | |
| SCHEMBL19692134 | 0.69 | PARP1 (0.43) | LMNAGLATDP1ALDH1A1GAA | |
| SCHEMBL20688413 | 0.69 | LMNA (0.41) | LMNAGLATDP1ALDH1A1GAA | |
| SCHEMBL4662853 | 0.68 | CRBN (0.52) | CRBNDDB1KDM4EPKM | |
| SCHEMBL35210773 | 0.68 | KDM4E (0.51) | LMNAGLATDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080044425-A1 | POLYPEPTIDES HAVING PHOSPHOLIPASE A2 ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-02-21 | — | — | US | claimed |
| US-20080015165-A1 | NOVEL POLYPEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-17 | — | — | US | claimed |
| US-7291491-B2 | Having poly-N-acetyllactosamine sugar chains synthesis-related activity; use in antiinflammation, antiinfection, inhibition of cancer metastasis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-11-06 | — | — | US | claimed |
| JP-3739785-B2 | — | — | 2006-01-25 | — | — | JP | claimed |
| US-20040265802-A9 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | FROEHLER BRIAN (US) | 2004-12-30 | — | — | US | claimed |
| US-20040014089-A1 | Polypeptides having phospholipase a2 activity | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2004-01-22 | — | — | US | claimed |
| US-20030170680-A1 | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines | FROEHLER BRIAN (US) | 2003-09-11 | — | — | US | claimed |
| US-20030166208-A1 | Novel polypeptides | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-09-04 | — | — | US | claimed |
| EP-1329511-A1 | POLYPEPTIDE HAVING PHOSPHOLIPASE A2 ACTIIVTY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-07-23 | — | — | EP | claimed |
| US-20030096980-A1 | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines | ISIS PHARMACEUTICALS, INC. | 2003-05-22 | — | — | US | claimed |
| EP-0637965-B1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | ISIS PHARMACEUTICALS INC (US) | 2002-10-16 | — | — | EP | claimed |
| EP-1162269-A1 | NOVEL POLYPEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-12-12 | — | — | EP | claimed |
| EP-1103604-A1 | NOVEL POLYPEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-05-30 | — | — | EP | claimed |
| WO-1999052906-A1 | SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | claimed |
| EP-0937775-A2 | Beta 1,3-N-acetylglucosaminyltransferase, DNA encoding it and its use | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-08-25 | — | — | EP | claimed |
| EP-0637965-A4 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES. | GILEAD SCIENCES INC (US) | 1996-01-24 | — | — | EP | claimed |
| EP-0637965-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1995-02-15 | — | — | EP | claimed |
| WO-1993010820-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1993-06-10 | — | — | WO | claimed |
| CN-114828890-A | Treatment of diabetes with stem cell migration agent | 比奥兹普科德公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-1999052906-A1 | SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030170680-A1 | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines | NUDT1, DHX15, DDX5 | CRBN 2611/4885DDB1 150/4885LMNA 1678/4885 |
| US-20040265802-A9 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | NUDT1, DHX15, DDX5 | CRBN 2611/4885DDB1 150/4885LMNA 1678/4885 |
| US-20030096980-A1 | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines | NUDT1, DHX15, DDX5 | CRBN 2611/4885DDB1 150/4885LMNA 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.