Zuretinol

Zuretinol

SCHEMBL254333

CC1=C(/C=C/C(C)=C\C=C\C(C)=C\CO)C(C)(C)CCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
MAPT P10636 7/20 1.00
CYP3A4 P08684 6/20 1.00
APP P05067 4/20 1.00
SNCA P37840 4/20 1.00
ALOX15 P16050 3/20 1.00
MAPK1 P28482 3/20 1.00
RBP4 P02753 3/20 1.00
TSHR P16473 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
NR1I2 O75469 1/20 1.00
USP2 O75604 1/20 1.00
PTGS1 P23219 4/20 0.80
SLCO1B3 Q9NPD5 2/20 0.80
SLCO1B1 Q9Y6L6 2/20 0.80
LMNA P02545 2/20 0.80
DRD3 P35462 2/20 0.80
TDP1 Q9NUW8 2/20 0.73
TP53 P04637 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Retinol SCHEMBL15592 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1580302 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3113 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL19660979 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3112 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1433566 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL15593 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL8360234 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL14619410 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL17226 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2082 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731618-A2 NOVEL CO-DRUG, CO-ADMINISTRATION, AND SEQUENTIAL ADMINISTRATION OF SELECTIVE TTR LIGAND AND C20-D3-RETINOL The Trustees Of Columbia University In The City Of New York (US) 2026-04-29 EP claimed
EP-4731204-A2 SELECTIVE RBP4 ANTAGONIST AND C20-D3-RETINOL FOR TREATING MACULAR DEGENERATION, NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD), AND GOUTY ARTHRITIS (GOUT) The Trustees Of Columbia University In The City Of New York (US) 2026-04-29 EP claimed
EP-4731619-A2 NOVEL CO-DRUG, CO-ADMINISTRATION, AND SEQUENTIAL ADMINISTRATION OF BISPECIFIC RBP4/TTR LIGAND AND C20-D3-RETINOL The Trustees Of Columbia University In The City Of New York (US) 2026-04-29 EP claimed
EP-4626260-A2 FERMENTATIVELY-PRODUCED RETINOID CONTAINING COMPOSITIONS, AND THE METHDOS OF MAKING AND USING THE SAME DSM IP Assets B.V. (NL) 2025-10-08 EP claimed
US-20250305024-A1 RELATIVE POTENCY ASSAY FOR VIRAL VECTOR ENCODING ISOMEROHYDROLASES SPARK THERAPEUTICS, INC. 2025-10-02 US claimed
US-12359239-B2 Relative potency assay for viral vector encoding isomerohydrolases SPARK THERAPEUTICS, INC. (US) 2025-07-15 US claimed
US-12329788-B2 Synbiotic compositions EVONIK OPERATIONS GMBH (DE) 2025-06-17 US claimed
EP-3784807-B1 SYNBIOTIC COMPOSITIONS EVONIK OPERATIONS GMBH (DE) 2025-06-04 EP claimed
US-12201956-B2 Tunable process for silica capsules/spheres preparation and their use PHARMA IN SILICA LABORATORIES INC. (CA) 2025-01-21 US claimed
US-20250009633-A1 PERSONAL CARE COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2025-01-09 US claimed
EP-1384482-A1 EXTERNAL SKIN COMPOSITIONS Kanebo, Limited (JP) 2004-01-28 EP claimed
EP-1383379-A1 RESTORATION OF CANCER-SUPPRESSING FUNCTIONS TO NEOPLASTIC CELLS THROUGH DNA HYPOMETHYLATION SuperGen, Inc. (US) 2004-01-28 EP claimed
WO-2002085400-A1 COMPOSITIONS AND METHODS FOR REESTABLISHING GENE TRANSCRIPTION THROUGH INHIBITION OF DNA METHYLATION AND HISTONE DEACETYLASE SUPERGEN, INC. (US) 2002-10-31 WO claimed
WO-2002067681-A1 RESTORE CANCER-SUPPRESSING FUNCTIONS TO NEOPLASTIC CELLS THROUGH DNA HYPOMETHYLATION SUPERGEN, INC. (US) 2002-09-06 WO claimed
US-20020114809-A1 Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation ASTEX PHARMACEUTICALS, INC. 2002-08-22 US claimed
EP-0666076-B1 Water in oil emulsion containing retinol OREAL (FR) 1998-12-23 EP claimed
US-5518914-A Growth medium containing a complex of prealbumin, a retinoid and retinol-binding protein used to enhance B cell growth SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-05-21 US claimed
EP-0664821-A1 LATENT STORE. SABET HUSCHANG (DE) 1995-08-02 EP claimed
WO-1994009081-A1 LATENT STORE SABET HUSCHANG (DE) 1994-04-28 WO claimed
WO-1991001745-A1 GROWTH FACTORS CONTAINING VITAMIN A OR OTHER RETINOIDS AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1991-02-21 WO claimed