Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MARS1 | P56192 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541239 | 0.91 | ATM (0.42) | ADKALDH1A1ATMSMN1; SMN2STING1 | |
| SCHEMBL12238556 | 0.91 | ATM (0.42) | ADKALDH1A1ATMSMN1; SMN2STING1 | |
| SCHEMBL2548233 | 0.86 | ALDH1A1 (0.39) | ADKALDH1A1ATMLMNASMN1; SMN2 | |
| SCHEMBL2546377 | 0.84 | ADK (0.37) | ADKALDH1A1ATMSTING1MARS1 | |
| SCHEMBL2548230 | 0.83 | MARS1 (0.39) | ADKALDH1A1ATMLMNASMN1; SMN2 | |
| SCHEMBL2548239 | 0.82 | YAP1 (0.35) | ADKSTING1DOT1LMARS1 | |
| SCHEMBL15633431 | 0.80 | FGFR1 (0.39) | ADKALDH1A1 | |
| SCHEMBL15633610 | 0.80 | FGFR1 (0.39) | ADKALDH1A1 | |
| SCHEMBL15633591 | 0.80 | FGFR1 (0.39) | ADKALDH1A1 | |
| SCHEMBL15633478 | 0.80 | ATM (0.40) | ADKALDH1A1ATMDOT1LCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940313-B2 | Tyrosine-based prodrugs of antiviral agents | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | TYMP, MTAP, TK1 | ADK 80/4885ALDH1A1 3139/4885ATM 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.