Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284436 | 0.84 | ALDH1A1 (0.42) | ALDH1A1IDO1AGXTTTRKDM4E | |
| SCHEMBL25432867 | 0.79 | KMO (0.37) | KMOPTGS2 | |
| SCHEMBL30688105 | 0.79 | KMO (0.37) | KMOPTGS2 | |
| SCHEMBL12086099 | 0.76 | ALDH1A1 (0.33) | ALDH1A1IDO1AGXTTTRKDM4E | |
| SCHEMBL2940929 | 0.76 | ALDH1A1 (0.39) | ALDH1A1IDO1AGXTTTRKDM4E | |
| SCHEMBL9135463 | 0.75 | ALDH1A1 (0.52) | ALDH1A1IDO1AGXTTTRKDM4E | |
| SCHEMBL2724713 | 0.75 | ALDH1A1 (0.35) | ALDH1A1IDO1AGXTTTRKDM4E | |
| SCHEMBL6281065 | 0.75 | ALDH1A1 (0.35) | ALDH1A1IDO1AGXTTTRKDM4E | |
| SCHEMBL12086169 | 0.75 | NFE2L2 (0.34) | ALDH1A1KDM4ECA1CA2HPGD | |
| SCHEMBL5043154 | 0.72 | CA1 (0.38) | ALDH1A1CA1CA2LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260068883-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-12302900-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20240130365-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2024-04-25 | — | — | US | disclosed |
| US-11889833-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2024-02-06 | — | — | US | disclosed |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| WO-2023137309-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11889833-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PNPO, PPIF | ALDH1A1 690/4885IDO1 450/4885AGXT 134/4885 |
| US-20240130365-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PNPO, PPIF | ALDH1A1 690/4885IDO1 450/4885AGXT 134/4885 |
| US-12302900-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PNPO, PPIF | ALDH1A1 690/4885IDO1 450/4885AGXT 134/4885 |
| US-20260068883-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, CYC1, CBR3 | ALDH1A1 773/4885IDO1 848/4885AGXT 296/4885 |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PNPO, PPIF | ALDH1A1 690/4885IDO1 450/4885AGXT 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.