Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.54 |
| ▸ | TK1 | P04183 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | POLD1 | P28340 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255504 | 0.88 | TK1 (0.56) | TYMSTK1POLBRNASE1POLA1 | |
| SCHEMBL2543582 | 0.87 | TYMS (0.63) | TYMSTK1POLB | |
| SCHEMBL8515502 | 0.85 | TK1 (0.50) | TYMSTK1POLBRNASE1POLA1 | |
| SCHEMBL8424441 | 0.85 | RNASE1 (0.53) | TYMSTK1RNASE1 | |
| SCHEMBL288740 | 0.82 | TK1 (0.74) | TYMSTK1POLBPOLA1POLD1 | |
| SCHEMBL21068055 | 0.82 | TK1 (0.74) | TYMSTK1POLBPOLA1POLD1 | |
| SCHEMBL7038209 | 0.82 | TK1 (0.74) | TYMSTK1POLBPOLA1POLD1 | |
| SCHEMBL7243145 | 0.82 | TK1 (0.62) | TK1POLBRNASE1POLA1POLD1 | |
| SCHEMBL3063249 | 0.80 | TYMS (0.68) | TYMSTK1POLB | |
| SCHEMBL8428624 | 0.80 | TYMS (0.68) | TYMSTK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267044-A1 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | FRANCISKOVICH PHILLIP P | 2010-10-21 | — | — | US | claimed |
| EP-2084294-A2 | STERILIZATION INDICATOR | American Sterilizer Company (US) | 2009-08-05 | — | — | EP | claimed |
| EP-2084293-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2009-08-05 | — | — | EP | claimed |
| WO-2008082728-A2 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| WO-2008079469-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-03 | — | — | WO | claimed |
| US-6787327-B2 | ENCODED BY ISOLATED NUCLEIC ACID; HIGH THROUGHPUT ENZYMATIC ASSAY; SCREENING FOR MODULATORS OF ENZYMATIC ACTIVITY | KELK GRADUATE OF APPLIED LIFE SCIENCES | 2004-09-07 | — | — | US | claimed |
| US-20030124587-A1 | Human tyrosine-DNA phosphodiesterase variant polypeptides and methods of use therefor | KECK GRADUATE INSTITUTE OF APPLIED LIFE SCIENCES | 2003-07-03 | — | — | US | claimed |
| WO-2003031579-A2 | HUMAN TYROSINE-DNA PHOSPHODIESTERASE VARIANT POLYPEPTIDES AND METHODS OF USE THEREFOR | KECK GRADUATE INSTITUTE OF APPLIED LIFE SCIENCES (US) | 2003-04-17 | — | — | WO | claimed |
| CN-112930397-B | ENPP1 polypeptides and methods of use thereof | 耶鲁大学 | 2025-05-09 | — | — | CN | disclosed |
| US-12024700-B2 | Biological disinfection or sterilization indicator | TERRAGENE LLC (US) | 2024-07-02 | — | — | US | disclosed |
| CN-113993993-A | ENPP1 polypeptides and methods of use thereof | 耶鲁大学 | 2022-01-28 | — | — | CN | disclosed |
| US-20210179998-A1 | BIOLOGICAL DISINFECTION OR STERILIZATION INDICATOR | TERRAGENE LLC (US) | 2021-06-17 | — | — | US | disclosed |
| CN-112930397-A | ENPP1 polypeptides and methods of use thereof | 耶鲁大学 | 2021-06-08 | — | — | CN | disclosed |
| US-11001799-B2 | Biological disinfection or sterilization indicator | TERRAGENE LLC (US) | 2021-05-11 | — | — | US | disclosed |
| WO-2003031579-A2 | HUMAN TYROSINE-DNA PHOSPHODIESTERASE VARIANT POLYPEPTIDES AND METHODS OF USE THEREFOR | KECK GRADUATE INSTITUTE OF APPLIED LIFE SCIENCES (US) | 2003-04-17 | — | — | WO | disclosed |
| EP-0371682-B1 | Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator | MINNESOTA MINING & MFG (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5418167-A | Sterilization indicator | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-23 | — | — | US | disclosed |
| US-5252484-A | Determination of efficiency of sterilization cycle | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| US-5223401-A | Colorimetric analysis; substrate system producing detectable enzyme-modified product | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| US-5073488-A | Using active enzyme | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-17 | — | — | US | disclosed |