Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 10/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496933 | 0.81 | TDP1 (0.50) | ALDH1A1TP53MAPTRAB9AL3MBTL1 | |
| SCHEMBL2025855 | 0.80 | RAB9A (0.49) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL18780592 | 0.80 | RAB9A (0.53) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL26828140 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TP53MAPTRAB9AL3MBTL1 | |
| SCHEMBL13996243 | 0.79 | RAB9A (0.51) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL9028343 | 0.76 | AKR1C3 (0.36) | ALDH1A1RAB9AL3MBTL1KDM4ELMNA | |
| SCHEMBL2904236 | 0.76 | TPSAB1 (0.49) | ALDH1A1TP53MAPTRAB9AL3MBTL1 | |
| SCHEMBL14446152 | 0.76 | L3MBTL1 (0.66) | ALDH1A1RAB9ANPC1L3MBTL1KDM4E | |
| SCHEMBL2904241 | 0.76 | TPSAB1 (0.49) | ALDH1A1TP53MAPTRAB9AL3MBTL1 | |
| SCHEMBL14567934 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TP53MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |