Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25439558 | 0.89 | BRD4 (0.44) | ALDH1A1HPGDKDM4EGAADHODH | |
| SCHEMBL25438118 | 0.73 | PDE10A (0.46) | ALDH1A1HPGDPTGFRPDE10ATSHR | |
| SCHEMBL30018125 | 0.72 | ALDH1A1 (0.44) | ALDH1A1LDHAHPGDKDM4EHSD17B10 | |
| SCHEMBL14252651 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LDHAHPGDKDM4EHSD17B10 | |
| SCHEMBL6016298 | 0.72 | MEN1 (0.47) | ALDH1A1LDHAHPGDKDM4EDHODH | |
| SCHEMBL27802674 | 0.71 | PTPN1 (0.46) | LDHADHODH | |
| SCHEMBL7057448 | 0.70 | ACMSD (0.56) | — | |
| SCHEMBL9784598 | 0.70 | ALDH1A1 (0.51) | ALDH1A1LDHAHPGDKDM4EHSD17B10 | |
| SCHEMBL5532405 | 0.69 | ALDH1A1 (0.54) | ALDH1A1LDHAKDM4EHSD17B10PDE10A | |
| SCHEMBL25439559 | 0.69 | GAA (0.47) | ALDH1A1HPGDPTGFRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |