Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851277 | 0.74 | MGLL (0.46) | MGLLTSHRALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL23852183 | 0.71 | NPC1 (0.50) | MGLLALDH1A1SMN1; SMN2HRH3GAA | |
| SCHEMBL23851279 | 0.68 | MGLL (0.52) | MGLLALDH1A1SMN1; SMN2HRH3KDM4E | |
| SCHEMBL27973414 | 0.67 | SMN1; SMN2 (0.41) | MGLLALDH1A1SMN1; SMN2HRH3GAA | |
| SCHEMBL21294369 | 0.65 | HSD17B10 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL248107 | 0.64 | HTR7 (0.42) | TSHRALDH1A1KDM4EGAALMNA | |
| SCHEMBL8772213 | 0.63 | HTR7 (0.41) | TSHRALDH1A1KDM4EGAALMNA | |
| SCHEMBL27585578 | 0.63 | HTR7 (0.45) | TSHRALDH1A1KDM4EMAPK1LMNA | |
| SCHEMBL5200121 | 0.63 | MEN1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29806270 | 0.63 | ALDH1A1 (0.41) | MGLLALDH1A1SMN1; SMN2HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |