Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851277 | 0.89 | MGLL (0.46) | NPC1RAB9AMGLLGAASMN1; SMN2 | |
| SCHEMBL23851279 | 0.85 | MGLL (0.52) | NPC1RAB9AMGLLGAASMN1; SMN2 | |
| SCHEMBL27973414 | 0.82 | SMN1; SMN2 (0.41) | NPC1RAB9AMGLLGAASMN1; SMN2 | |
| SCHEMBL23803752 | 0.72 | NPC1 (0.57) | NPC1RAB9ALIPEGAASMN1; SMN2 | |
| SCHEMBL4269162 | 0.72 | GPR119 (0.55) | — | |
| SCHEMBL30150132 | 0.72 | GPR119 (0.55) | — | |
| SCHEMBL18343897 | 0.72 | NPC1 (0.68) | NPC1RAB9ALIPEGAASMN1; SMN2 | |
| SCHEMBL6880743 | 0.71 | NPC1 (0.88) | NPC1RAB9AMGLLGAASMN1; SMN2 | |
| SCHEMBL25438423 | 0.71 | RIPK1 (0.37) | MGLLGAASMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL28731835 | 0.70 | RAB9A (0.48) | NPC1RAB9AMGLLGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |