Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23852183 | 0.89 | NPC1 (0.50) | MGLLGAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL23851279 | 0.85 | MGLL (0.52) | MGLLGAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL27973414 | 0.82 | SMN1; SMN2 (0.41) | MGLLGAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL25438423 | 0.74 | RIPK1 (0.37) | MGLLGAASMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL23803750 | 0.72 | GAA (0.47) | GAASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4269162 | 0.72 | GPR119 (0.55) | — | |
| SCHEMBL30150132 | 0.72 | GPR119 (0.55) | — | |
| SCHEMBL28731835 | 0.70 | RAB9A (0.48) | MGLLGAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28731834 | 0.70 | MGLL (0.45) | MGLLGAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL248107 | 0.70 | HTR7 (0.42) | GAAALDH1A1TSHRFAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |