Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442424 | 0.81 | HRH4 (0.47) | ALDH1A1SMN1; SMN2HRH4 | |
| SCHEMBL16306950 | 0.79 | VCAM1 (0.43) | LMNAALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL24254514 | 0.76 | ALDH1A1 (0.54) | LMNAALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL12338346 | 0.74 | ALDH1A1 (0.54) | LMNAALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL14374413 | 0.72 | MAPT (0.64) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL12338040 | 0.72 | NPC1 (0.64) | ALDH1A1NPC1SMN1; SMN2TNFRAB9A | |
| SCHEMBL25442640 | 0.71 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2RAB9AKDM4EVCAM1 | |
| SCHEMBL3529447 | 0.70 | MAPT (0.53) | LMNAALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL13243780 | 0.70 | KDM4E (0.39) | LMNAALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL20488840 | 0.69 | VCAM1 (0.50) | LMNAALDH1A1HTTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | LMNA 2827/4885ALDH1A1 3889/4885HTT 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.