Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442803 | 0.81 | LMNA (0.40) | HRH4ALDH1A1SMN1; SMN2 | |
| SCHEMBL25442683 | 0.81 | HRH4 (0.43) | HRH4AKR1C3AKR1C2ALDH1A1G6PD | |
| SCHEMBL20526546 | 0.81 | G6PD (0.50) | HRH4AKR1C3AKR1C2ALDH1A1G6PD | |
| SCHEMBL13176065 | 0.81 | LMNA (0.44) | HRH4ALDH1A1 | |
| SCHEMBL13995384 | 0.77 | KIF11 (0.44) | HRH4 | |
| SCHEMBL8947263 | 0.77 | LMNA (0.51) | HRH4AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL13889401 | 0.76 | BRD4 (0.43) | HRH4BRD4AKR1C3AKR1C2G6PD | |
| SCHEMBL25442640 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2 | |
| SCHEMBL16972466 | 0.73 | ENPP2 (0.40) | HRH4BRD4AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL12560649 | 0.73 | BRD4 (0.46) | BRD4G6PDIDESMN1; SMN2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | HRH4 4593/4885BRD4 1406/4885AKR1C3 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.