SCHEMBL25445883

SCHEMBL25445883

Cc1ccc(-c2cc(C)c(CC(C)(C)C)c[n+]2C)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25445885 0.91 GAA (0.30) GAAMAPT
SCHEMBL26015165 0.85 KDM4E (0.30) RAB9ASMN1; SMN2MAPT
SCHEMBL25445873 0.84 RIPK1 (0.31)
SCHEMBL25446030 0.83 MAPT (0.36) LMNAHTTRAB9ASMN1; SMN2GAA
SCHEMBL26014076 0.82 MAPT (0.30) RAB9ASMN1; SMN2GAAMAPT
SCHEMBL25445935 0.79 KDM4E (0.33) LMNAHTTRAB9ASMN1; SMN2GAA
SCHEMBL25445857 0.79 ESR1 (0.33) GAAMAPT
SCHEMBL25446150 0.78 ESR2 (0.33) LMNAHTTRAB9ASMN1; SMN2
SCHEMBL25445734 0.77 MAPT (0.37) LMNAHTTRAB9ASMN1; SMN2GAA
SCHEMBL25445947 0.77 GAA (0.33) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
EP-4329463-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-02-28 EP disclosed
EP-4001287-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-01-17 EP disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
EP-3771717-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-05-17 EP disclosed
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed
US-11639363-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-05-02 US disclosed
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 LMNA 2285/4885HTT 4331/4885RAB9A 281/4885
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG LMNA 1110/4885HTT 3497/4885RAB9A 1325/4885
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 LMNA 2995/4885HTT 1214/4885RAB9A 2280/4885
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, TPO LMNA 2706/4885HTT 656/4885RAB9A 3415/4885
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, SSB LMNA 1460/4885HTT 4235/4885RAB9A 528/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 LMNA 1533/4885HTT 2484/4885RAB9A 1557/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 LMNA 1300/4885HTT 3280/4885RAB9A 676/4885
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, MCOLN3 LMNA 743/4885HTT 3899/4885RAB9A 898/4885
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 LMNA 984/4885HTT 3582/4885RAB9A 1432/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP LMNA 2541/4885HTT 2222/4885RAB9A 1853/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG LMNA 2246/4885HTT 937/4885RAB9A 1884/4885
US-11639363-B2 Organic electroluminescent materials and devices LEF1, L1CAM, SSB LMNA 552/4885HTT 3919/4885RAB9A 925/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 LMNA 2276/4885HTT 4274/4885RAB9A 257/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 LMNA 2023/4885HTT 4568/4885RAB9A 252/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 LMNA 1582/4885HTT 1268/4885RAB9A 378/4885
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RPS4X, SOD1, CNKSR1 LMNA 1451/4885HTT 4478/4885RAB9A 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.