SCHEMBL25445955

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25445946	0.90	GABRA1 (0.34)	GABRA1GABRB2ARNPC1CASP3
	SCHEMBL25884873	0.90	GABRA1 (0.34)	GABRA1GABRB2ARNPC1CASP3
	SCHEMBL26023552	0.86	AR (0.35)	GABRA1GABRB2ARNPC1RAB9A
	SCHEMBL26572336	0.83	AR (0.31)	GABRA1GABRB2AR
	SCHEMBL25455613	0.83	AR (0.31)	GABRA1GABRB2ARNPC1MEN1
	SCHEMBL26014286	0.83	NPC1 (0.33)	GABRA1GABRB2ARNPC1CASP3
	SCHEMBL26351722	0.83	MEN1 (0.31)	GABRA1GABRB2ARRAB9AMEN1
	SCHEMBL26013136	0.83	NPC1 (0.33)	GABRA1GABRB2ARNPC1CASP3
	SCHEMBL25445989	0.83	RAB9A (0.36)	ARNPC1CASP3RAB9ASMN1; SMN2
	SCHEMBL25445956	0.82	GAA (0.33)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.