Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.52 |
| ▸ | KLHL20 | Q9Y2M5 | 1/20 | 0.50 |
| ▸ | LDLR | P01130 | 2/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | KLK2 | P20151 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | CIB1 | Q99828 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455198 | 0.97 | KLKB1 (0.52) | KLKB1KLHL20LDLRPCSK9ITGB3 | |
| SCHEMBL25459225 | 0.95 | KLKB1 (0.48) | KLKB1KLHL20LDLRPCSK9ITGB3 | |
| SCHEMBL25455641 | 0.95 | KLKB1 (0.51) | KLKB1KLHL20ITGB3ITGB1ITGAV | |
| SCHEMBL25455166 | 0.95 | KLKB1 (0.51) | KLKB1KLHL20ITGB3ITGB1ITGAV | |
| SCHEMBL25455193 | 0.95 | ITGB3 (0.52) | KLKB1KLHL20ITGB3ITGB1ITGAV | |
| SCHEMBL25455170 | 0.94 | CIB1 (0.51) | KLKB1KLHL20ITGB3ITGB1ITGAV | |
| SCHEMBL25455212 | 0.94 | KLKB1 (0.50) | KLKB1KLHL20LDLRPCSK9ITGB3 | |
| SCHEMBL25457027 | 0.94 | KLHL20 (0.51) | KLKB1KLHL20LDLRPCSK9ITGB3 | |
| SCHEMBL25455512 | 0.94 | KLKB1 (0.50) | KLKB1LDLRPCSK9ITGB3ITGB1 | |
| SCHEMBL25455205 | 0.94 | ITGB3 (0.52) | KLKB1KLHL20LDLRPCSK9ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | QUANTUM INTELLIGENCE CORP. (KR) | 2023-05-11 | — | — | US | disclosed |
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | QUANTUM INTELLIGENCE CORP. (KR) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | ITGB7, ITGAM, ITGA4 | KLKB1 1100/4885KLHL20 4508/4885LDLR 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.