Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.56 |
| ▸ | SMO | Q99835 | 2/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790067 | 1.00 | TGFBR1 (0.56) | TGFBR1SMOASIC3PIM1FAAH | |
| SCHEMBL18790842 | 0.87 | TGFBR1 (0.45) | TGFBR1SMOASIC3PIM1MAP4K4 | |
| SCHEMBL18790497 | 0.87 | RXRA (0.47) | TGFBR1SMOASIC3PIM1FAAH | |
| SCHEMBL18790543 | 0.87 | ASIC3 (0.47) | TGFBR1SMOASIC3PIM1FAAH | |
| SCHEMBL25456048 | 0.86 | ASIC3 (0.50) | TGFBR1SMOASIC3FAAHDHODH | |
| SCHEMBL29854571 | 0.86 | ASIC3 (0.61) | TGFBR1SMOASIC3PIM1MAP4K4 | |
| SCHEMBL24291931 | 0.86 | ASIC3 (0.61) | TGFBR1SMOASIC3PIM1MAP4K4 | |
| SCHEMBL17694751 | 0.86 | ASIC3 (0.61) | TGFBR1SMOASIC3PIM1MAP4K4 | |
| SCHEMBL4897325 | 0.84 | KMO (0.55) | TGFBR1DHODHMAP4K4RXRARXRB | |
| SCHEMBL4901264 | 0.84 | RXRA (0.57) | SMOMAP4K4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11653558-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11653558-B2 | Organic electroluminescent materials and devices | OSBPL3, LBR, LOXL3 | TGFBR1 1435/4885SMO 3558/4885ASIC3 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.