SCHEMBL2545657

SCHEMBL2545657

CC(C)O[Si](OC(C)C)(OC(C)C)c1cccc2cc3ccccc3cc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.36
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 4/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 3/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 3/20 0.33
CYP1A2 P05177 2/20 0.33
HPGD P15428 1/20 0.33
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
TLR8 Q9NR97 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.31
BTK Q06187 1/20 0.31
UGT2B7 P16662 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895557 0.84 KDM4E (0.39) ALDH1A1KDM4EMAPTHSD17B10CYP1A2
SCHEMBL108035 0.84 KDM4E (0.39) ALDH1A1KDM4EMAPTHSD17B10CYP1A2
SCHEMBL29503121 0.80 NQO1 (0.44) NQO1ALDH1A1KDM4EGAAMAPT
SCHEMBL1616108 0.80 NQO1 (0.44) NQO1ALDH1A1KDM4EGAAMAPT
SCHEMBL6748539 0.79 NQO1 (0.42) NQO1ALDH1A1KDM4EGAAMAPT
SCHEMBL2550554 0.78 HPRT1 (0.47) ALDH1A1KDM4EMAPTHSD17B10CYP1A2
SCHEMBL20872881 0.77 TRPM4 (0.38) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL426113 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL27676100 0.77 ALDH1A1 (0.38) NQO1ALDH1A1KDM4EGAAMAPT
SCHEMBL935775 0.76 NQO1 (0.36) NQO1ALDH1A1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
EP-2239301-B1 SILOXANE RESIN COMPOSITIONS TORAY INDUSTRIES (JP) 2016-04-27 EP disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
EP-2239301-A1 SILOXANE RESIN COMPOSITIONS Toray Industries, Inc. (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD NQO1 3752/4885ALDH1A1 599/4885KDM4E 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.