SCHEMBL2550554

SCHEMBL2550554

CC(C)O[Si](OC(C)C)(OC(C)C)c1cccc2c1ccc1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.47
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP2A6 P11509 2/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
APEX1 P27695 1/20 0.38
MAPK1 P28482 1/20 0.38
PMP22 Q01453 1/20 0.38
CYP1A2 P05177 4/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PAX8 Q06710 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 2/20 0.35
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108035 0.90 KDM4E (0.39) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL29895557 0.90 KDM4E (0.39) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL20872881 0.83 TRPM4 (0.38) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL2546879 0.81 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL2545657 0.78 NQO1 (0.36) ALDH1A1HSD17B10MAPTLMNACYP1A2
SCHEMBL2552884 0.78 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1TSHRMAPT
SCHEMBL3479945 0.77 HPRT1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL29777494 0.77 HPRT1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL426113 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL20658014 0.75 KDM4E (0.39) ALDH1A1HSD17B10TDP1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
EP-2239301-B1 SILOXANE RESIN COMPOSITIONS TORAY INDUSTRIES (JP) 2016-04-27 EP disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
EP-2239301-A1 SILOXANE RESIN COMPOSITIONS Toray Industries, Inc. (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD HPRT1 2773/4885ALDH1A1 599/4885HSD17B10 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.