SCHEMBL25459653

SCHEMBL25459653

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4nc(-c5cccc(-c6cccc7c6sc6c(-c8nc9ccccc9s8)cccc67)c5)oc4c3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.41
KDM4E B2RXH2 5/20 0.41
NPC1 O15118 5/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 5/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
NFKB1 P19838 4/20 0.41
NFKB2 Q00653 4/20 0.41
RELA Q04206 4/20 0.41
HPGD P15428 3/20 0.41
GAA P10253 3/20 0.41
TP53 P04637 3/20 0.41
LMNA P02545 2/20 0.41
STAT1 P42224 1/20 0.41
GFER P55789 1/20 0.41
GPR119 Q8TDV5 1/20 0.39
VSIR Q9H7M9 5/20 0.37
APP P05067 3/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25459650 0.95 GPR119 (0.41) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459436 0.93 HPSE (0.40) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459696 0.89 VSIR (0.44) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459695 0.88 ALOX5 (0.46) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459435 0.88 RAB9A (0.39) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459644 0.88 NPC1 (0.44) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL21891096 0.87 RAB9A (0.45) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459721 0.85 APP (0.52) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL21890971 0.85 VSIR (0.44) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25459713 0.85 MAPT (0.45) RAB9AKDM4ENPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4181655-A1 ORGANIC LIGHT EMITTING ELEMENT LG Display Co., Ltd. (KR) 2023-05-17 EP disclosed
US-20230145469-A1 ORGANIC LIGHT EMITTING ELEMENT LG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
US-20230145469-A1 ORGANIC LIGHT EMITTING ELEMENT LG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed