Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 4/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546077 | 0.89 | SCN1A (0.40) | GPR119SCDSCN1ASCN8AUTS2R | |
| SCHEMBL2549095 | 0.85 | GPR119 (0.39) | GPR119SCDSCN1ASCN8A | |
| SCHEMBL2548234 | 0.85 | GPR119 (0.40) | GPR119SCDSCN1ASCN8A | |
| SCHEMBL2544043 | 0.84 | GPR119 (0.40) | GPR119SCD | |
| SCHEMBL1007123 | 0.80 | GPR119 (0.42) | GPR119UTS2R | |
| SCHEMBL12239182 | 0.79 | ALDH1A1 (0.51) | GPR119SCDSCN1ASCN8A | |
| SCHEMBL1006689 | 0.77 | GPR119 (0.40) | GPR119SCDSCN1ASCN8A | |
| SCHEMBL1005456 | 0.77 | GPR119 (0.45) | GPR119SCN1ASCN8A | |
| SCHEMBL1003971 | 0.75 | SCD (0.46) | GPR119SCD | |
| SCHEMBL12239186 | 0.75 | SCD (0.42) | GPR119SCDSCN1ASCN8AUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | GPR119 1/4885SCD 1145/4885SCN1A 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.