Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546392 | 0.85 | L3MBTL1 (0.61) | L3MBTL1BLMTDP1ALDH1A1MEN1 | |
| SCHEMBL7716422 | 0.78 | L3MBTL1 (0.71) | L3MBTL1MAPK1BLMTDP1ALDH1A1 | |
| SCHEMBL11704633 | 0.76 | L3MBTL1 (0.67) | L3MBTL1MAPK1BLMTP53KDM4E | |
| SCHEMBL9028 | 0.76 | TDP1 (0.60) | L3MBTL1MAPK1BLMTDP1ALDH1A1 | |
| SCHEMBL16907485 | 0.74 | NPSR1 (0.61) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29739599 | 0.74 | NPSR1 (0.61) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29739697 | 0.74 | KMT2A (0.70) | L3MBTL1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL5416952 | 0.73 | ALDH1A1 (0.59) | TP53TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL5154376 | 0.73 | GRIK1 (0.61) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11184124 | 0.73 | NPC1 (0.63) | L3MBTL1TDP1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121602-A1 | PROCESS FOR PREPARATION OF DIBENZOTHIAZEPINONE COMPOUNDS | HIKAL LIMITED (IN) | 2011-10-06 | — | — | WO | disclosed |