SCHEMBL25464951

SCHEMBL25464951

CC(C)Oc1ccccc1-c1ccc(Oc2[nH]nnc2C(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKAB2 O43741 1/20 0.41
▸ PRKAG1 P54619 1/20 0.41
▸ PRKAA2 P54646 1/20 0.41
▸ PRKAA1 Q13131 1/20 0.41
▸ PRKAG3 Q9UGI9 1/20 0.41
▸ PRKAG2 Q9UGJ0 1/20 0.41
▸ PRKAB1 Q9Y478 1/20 0.41
▸ ALOX15 P16050 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ MCL1 Q07820 4/20 0.39
▸ PPARG P37231 3/20 0.38
▸ PPARA Q07869 3/20 0.38
▸ FFAR4 Q5NUL3 1/20 0.37
▸ ABL1 P00519 1/20 0.37
▸ BCL2 P10415 2/20 0.37
▸ MDM2 Q00987 2/20 0.37
▸ CTSA P10619 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25464132 0.93 ALOX15 (0.39) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL24154465 0.89 DRD1 (0.47) PPARGPPARAFFAR4PTGS2CAMKK2
SCHEMBL25463453 0.84 DRD1 (0.47) PPARGPPARAFFAR4PTGS2ADRA2A
SCHEMBL21312600 0.82 PPARG (0.43) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL21296854 0.80 HAO1 (0.44) PRKAG1PRKAA1PRKAB1MCL1KDM4E
SCHEMBL21312599 0.80 ALPL (0.42) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL21296864 0.80 PPARG (0.43) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL25463638 0.80 DRD1 (0.44) PPARGPPARAFFAR4PTGS2
SCHEMBL23320028 0.78 PPARG (0.48) MCL1PPARGPPARA
SCHEMBL29968357 0.78 PPARG (0.48) MCL1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO PRKAB2 3843/4885PRKAG1 2945/4885PRKAA2 2934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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