Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 4/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520523 | 0.83 | MAP3K12 (0.38) | MAP3K12 | |
| SCHEMBL23264167 | 0.78 | USP1 (0.33) | USP1CYP1A2LRRK2 | |
| SCHEMBL25463480 | 0.77 | MAP3K12 (0.40) | USP1MAP3K12 | |
| SCHEMBL25517541 | 0.75 | MAP3K12 (0.33) | MAP3K12 | |
| SCHEMBL25464158 | 0.71 | MMP13 (0.40) | — | |
| SCHEMBL18865878 | 0.70 | USP1 (0.47) | USP1 | |
| SCHEMBL31625133 | 0.70 | USP1 (0.49) | USP1 | |
| SCHEMBL27086978 | 0.70 | USP1 (0.47) | USP1 | |
| SCHEMBL22165630 | 0.70 | USP1 (0.43) | USP1 | |
| SCHEMBL24936214 | 0.68 | WDR5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083297-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |