Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25467002 | 0.83 | USP1 (0.34) | MAP3K12 | |
| SCHEMBL25517541 | 0.83 | MAP3K12 (0.33) | MAP3K12 | |
| SCHEMBL24936214 | 0.82 | WDR5 (0.41) | WDR5KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL25522267 | 0.80 | MAP3K12 (0.36) | MAP3K12WDR5 | |
| SCHEMBL23264473 | 0.77 | MAP3K12 (0.35) | MAP3K12 | |
| SCHEMBL23264163 | 0.76 | MAP3K12 (0.53) | MAP3K12 | |
| Hydrochloric Acid SCHEMBL23389302 | 0.72 | WDR5 (0.39) | MAP3K12WDR5KDM4ENPC1ALDH1A1 | |
| SCHEMBL25464158 | 0.72 | MMP13 (0.40) | — | |
| SCHEMBL23264161 | 0.70 | MAP3K12 (0.33) | MAP3K12 | |
| SCHEMBL25518604 | 0.70 | DGAT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |