Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520523 | 0.83 | MAP3K12 (0.38) | MAP3K12 | |
| SCHEMBL25467002 | 0.75 | USP1 (0.34) | MAP3K12 | |
| SCHEMBL25522141 | 0.75 | GABRA2 (0.34) | GABRA2GABRB2PDE10A | |
| SCHEMBL25522267 | 0.72 | MAP3K12 (0.36) | MAP3K12 | |
| SCHEMBL23264161 | 0.72 | MAP3K12 (0.33) | MAP3K12 | |
| SCHEMBL24936214 | 0.71 | WDR5 (0.41) | — | |
| SCHEMBL25463482 | 0.71 | MAP3K12 (0.51) | MAP3K12 | |
| SCHEMBL23264473 | 0.67 | MAP3K12 (0.35) | MAP3K12 | |
| SCHEMBL23264163 | 0.66 | MAP3K12 (0.53) | MAP3K12 | |
| SCHEMBL31368695 | 0.65 | USP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |