Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25469275 | 0.84 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDATMCYP1A2 | |
| SCHEMBL7606949 | 0.84 | SIRT1 (0.32) | HSD17B10 | |
| SCHEMBL23462461 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDATMCYP1A2 | |
| SCHEMBL10744105 | 0.81 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDATMCYP1A2 | |
| SCHEMBL23462290 | 0.78 | ADRA1D (0.43) | ALDH1A1KDM4EHPGDATMCYP1A2 | |
| SCHEMBL7120249 | 0.75 | KMT2A (0.52) | ALDH1A1KDM4EMAPTKMT2AHTT | |
| SCHEMBL7757705 | 0.74 | KDM4E (0.43) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL26748930 | 0.72 | TSHR (0.45) | ALDH1A1KDM4ECYP2C9CYP2C19MAPT | |
| SCHEMBL38662922 | 0.71 | ACHE (0.45) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL23461083 | 0.71 | ACHE (0.45) | ALDH1A1KDM4EHPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147360-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147360-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | ALDH1A1 1072/4885KDM4E 3906/4885HPGD 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.