SCHEMBL25469337

SCHEMBL25469337

Cc1cc(O)cc(C)c1C[C@H](N)C(=O)OBr

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 11/20 0.45
OPRM1 P35372 8/20 0.45
OPRK1 P41145 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5115242 0.85 OPRD1 (0.46) OPRD1OPRM1OPRK1
SCHEMBL5115246 0.85 OPRD1 (0.46) OPRD1OPRM1OPRK1
SCHEMBL30162392 0.85 CYP3A4 (0.46) OPRD1OPRM1OPRK1
Hydrochloric Acid SCHEMBL5775220 0.84 OPRD1 (0.46) OPRD1OPRM1OPRK1
Hydrochloric Acid SCHEMBL5775227 0.84 OPRD1 (0.46) OPRD1OPRM1OPRK1
SCHEMBL21096380 0.81 OPRM1 (0.47) OPRD1OPRM1OPRK1
SCHEMBL296690 0.80 SLC7A5 (0.50) OPRD1OPRM1OPRK1
SCHEMBL21890005 0.80 OPRM1 (0.47) OPRD1OPRM1OPRK1
SCHEMBL18710761 0.80 OPRK1 (0.47) OPRD1OPRM1OPRK1
SCHEMBL19891259 0.80 OPRM1 (0.47) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 OPRD1 3815/4885OPRM1 3513/4885OPRK1 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.