Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25470064 | 1.00 | TYMS (0.47) | TYMS | |
| SCHEMBL25470065 | 0.91 | TK1 (0.57) | — | |
| SCHEMBL8925580 | 0.84 | TK1 (0.59) | — | |
| SCHEMBL8925599 | 0.84 | TK1 (0.59) | — | |
| SCHEMBL13222053 | 0.84 | LMNA (0.58) | — | |
| SCHEMBL25469637 | 0.83 | — | — | |
| SCHEMBL25470068 | 0.82 | DNMT1 (0.42) | — | |
| SCHEMBL25469566 | 0.82 | DNMT1 (0.42) | — | |
| SCHEMBL29757418 | 0.82 | TK1 (0.58) | — | |
| SCHEMBL8926762 | 0.81 | TK1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348968-A1 | SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-11-02 | — | — | US | disclosed |
| US-11655502-B2 | Short pendant arm linkers for nucleotides in sequencing applications | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348968-A1 | SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS | POLRMT, POLM, POLN | TYMS 61/4885 |
| US-11655502-B2 | Short pendant arm linkers for nucleotides in sequencing applications | POLRMT, POLM, POLN | TYMS 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.