Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996937 | 0.81 | L3MBTL1 (0.47) | TAAR1SIGMAR1HTR2AHTTSMN1; SMN2 | |
| SCHEMBL10087662 | 0.81 | ALDH1A1 (0.47) | TAAR1SIGMAR1HTTSMN1; SMN2ADRB2 | |
| SCHEMBL23695828 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HTTSMN1; SMN2ADRB2LMNA | |
| SCHEMBL13532079 | 0.79 | TAAR1 (0.61) | TAAR1SIGMAR1HTTSMN1; SMN2ADRB2 | |
| SCHEMBL15031576 | 0.79 | LMNA (0.50) | TAAR1SIGMAR1HTTSMN1; SMN2ADRB2 | |
| SCHEMBL3084431 | 0.79 | TAAR1 (0.61) | TAAR1SIGMAR1HTTSMN1; SMN2ADRB2 | |
| SCHEMBL9911348 | 0.79 | LMNA (0.64) | SIGMAR1HTR2AHTTADRB2LMNA | |
| SCHEMBL255039 | 0.79 | GFER (0.52) | SIGMAR1HTTSMN1; SMN2ADRB2LMNA | |
| SCHEMBL20024425 | 0.79 | SIGMAR1 (0.53) | SIGMAR1HTTSMN1; SMN2ADRB2LMNA | |
| SCHEMBL2548456 | 0.78 | PYCR1 (0.48) | TAAR1SIGMAR1LMNACYP2D6PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112822948-A | TAAR receptor agonists for the treatment of alopecia | 应用生物学公司 | 2021-05-18 | — | — | CN | disclosed |
| WO-2012030986-A2 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |