SCHEMBL25475403

SCHEMBL25475403

CC(S)C(=O)OC1(c2ccccc2)CCNC1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.43
HTR2A P28223 1/20 0.41
OPRK1 P41145 4/20 0.34
OPRD1 P41143 3/20 0.34
HDAC1 Q13547 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
APOBEC3A P31941 2/20 0.33
APOBEC3G Q9HC16 2/20 0.33
OPRL1 P41146 1/20 0.32
PRCP P42785 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25475404 0.92 OPRM1 (0.39) OPRM1HTR2AOPRK1OPRD1APOBEC3A
SCHEMBL25475417 0.92 OPRM1 (0.48) OPRM1HTR2AOPRK1OPRD1HDAC1
SCHEMBL23870806 0.86 OPRM1 (0.43) OPRM1HTR2AOPRK1OPRD1HDAC1
SCHEMBL26785458 0.83 HTR2A (0.42) OPRM1HTR2AOPRK1OPRD1HDAC1
SCHEMBL3908513 0.81 HTR2A (0.46) OPRM1HTR2AOPRK1OPRD1OPRL1
SCHEMBL25475401 0.81 KDM1A (0.33) OPRM1SLC6A2SLC6A4SLC6A3
SCHEMBL24944641 0.80 OPRM1 (0.50) OPRM1HTR2AOPRK1OPRD1HDAC1
SCHEMBL25475412 0.80 OPRM1 (0.38) OPRM1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL26413266 0.79 OPRM1 (0.49) OPRM1HTR2AOPRK1OPRD1HDAC1
SCHEMBL25475405 0.78 MME (0.38) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230161255-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161255-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230152698-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed