Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.64 |
| ▸ | DRD1 | P21728 | 4/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.64 |
| ▸ | HTR2A | P28223 | 4/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.64 |
| ▸ | HRH1 | P35367 | 4/20 | 0.64 |
| ▸ | DRD3 | P35462 | 4/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perazine SCHEMBL29390464 | 0.88 | KDM1A (1.00) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| Perazine SCHEMBL147165 | 0.88 | KDM1A (1.00) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| Perazine SCHEMBL6644457 | 0.87 | KDM1A (0.97) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| Perazine SCHEMBL2237726 | 0.87 | KDM1A (0.97) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6859184 | 0.86 | KDM1A (0.94) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| Perazine SCHEMBL10531680 | 0.81 | KDM1A (0.84) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL4399786 | 0.81 | KDM1A (0.70) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10973127 | 0.81 | KDM1A (0.84) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2615404 | 0.79 | KDM1A (0.80) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL12083350 | 0.79 | FPR2 (0.89) | KDM1ALMNAMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552323-A1 | COMBINATION THERAPY | Follica, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011123218-A1 | COMBINATION THERAPY | FOLLICA, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| WO-2007041463-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |