Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 15/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25487994 | 0.90 | P2RX7 (0.35) | P2RX7KDM1ANR3C1 | |
| SCHEMBL25487997 | 0.88 | PRKCI (0.34) | PRKCI | |
| SCHEMBL25487531 | 0.87 | NR3C1 (0.37) | P2RX7NR3C1 | |
| SCHEMBL25487564 | 0.82 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL25487554 | 0.82 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL25487702 | 0.77 | MEN1 (0.36) | P2RX7 | |
| SCHEMBL25487709 | 0.77 | MEN1 (0.36) | P2RX7 | |
| SCHEMBL25487698 | 0.73 | BIRC2 (0.41) | P2RX7 | |
| SCHEMBL25487607 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL25487556 | 0.73 | P2RX7 (0.37) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655257-B2 | MK2 inhibitors, synthesis thereof, and intermediates thereto | CELGENE CAR LLC (BM) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655257-B2 | MK2 inhibitors, synthesis thereof, and intermediates thereto | WEE2, WEE1, CDK2 | P2RX7 3185/4885PRKCI 1145/4885KDM1A 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.