Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 5/20 | 0.55 |
| ▸ | ICMT | O60725 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244383 | 0.88 | TSHR (0.62) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL23701860 | 0.82 | PPARG (0.73) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL6116786 | 0.82 | TSHR (0.69) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL23701770 | 0.82 | ICMT (0.79) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL6131655 | 0.80 | TSHR (0.66) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL27099115 | 0.78 | ALDH1A1 (0.68) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL6242131 | 0.77 | ALDH1A1 (0.66) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL5337098 | 0.77 | TSHR (0.66) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL9765109 | 0.75 | HTR1D (0.65) | TSHRALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL25491588 | 0.75 | ICMT (0.52) | LMNANPSR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |