Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 10/20 | 0.43 |
| ▸ | NNMT | P40261 | 7/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25495952 | 0.93 | PRMT5 (0.47) | PRMT5NNMTWDR77 | |
| SCHEMBL25496133 | 0.93 | PRMT5 (0.47) | PRMT5NNMTWDR77 | |
| SCHEMBL25495954 | 0.86 | PRMT5 (0.47) | PRMT5NNMTWDR77 | |
| SCHEMBL25495950 | 0.82 | PRMT5 (0.38) | PRMT5NNMTWDR77 | |
| SCHEMBL25496131 | 0.82 | PRMT5 (0.38) | PRMT5NNMTWDR77 | |
| SCHEMBL29313467 | 0.80 | ADK (0.53) | PRMT5WDR77 | |
| SCHEMBL19344245 | 0.79 | ADK (0.41) | PRMT5NNMTWDR77 | |
| SCHEMBL25496027 | 0.79 | AHCY (0.59) | — | |
| SCHEMBL26327164 | 0.79 | AHCY (0.59) | — | |
| SCHEMBL29313461 | 0.77 | ADK (0.60) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, MAVS | PRMT5 1272/4885NNMT 1920/4885WDR77 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.