Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA6 | P23280 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838781 | 0.79 | LMNA (0.51) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL27968997 | 0.74 | LMNA (0.67) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL11837322 | 0.74 | LMNA (0.67) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL11837318 | 0.74 | LMNA (0.67) | LMNAAKR1B10AKR1B1CA12CA4 | |
| Benzyl Cinnamate SCHEMBL1871854 | 0.74 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA4 | |
| Benzyl Cinnamate SCHEMBL43213 | 0.74 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA4 | |
| Benzyl Cinnamate SCHEMBL901152 | 0.74 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL13552179 | 0.74 | LMNA (0.93) | LMNAAKR1B10AKR1B1CA12CA4 | |
| Benzyl Cinnamate SCHEMBL43212 | 0.74 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL24812776 | 0.74 | LMNA (0.45) | LMNAAKR1B10AKR1B1CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158153-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158153-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | MMP1, PIK3CA, AKT2 | LMNA 2101/4885AKR1B10 3253/4885AKR1B1 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.