Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301224 | 0.82 | KEAP1 (0.60) | KEAP1NFE2L2SMN1; SMN2TSHRCASP1 | |
| SCHEMBL23674282 | 0.82 | IDO1 (0.38) | CYP3A4CASP1SLC9A1ALDH1A1TDP1 | |
| SCHEMBL29795353 | 0.81 | SLC9A1 (0.46) | KEAP1NFE2L2CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL22666874 | 0.81 | SLC9A1 (0.46) | KEAP1NFE2L2CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL20298359 | 0.78 | ALDH1A1 (0.46) | KEAP1NFE2L2CYP3A4SMN1; SMN2SLC9A1 | |
| SCHEMBL24659358 | 0.78 | KEAP1 (0.42) | KEAP1NFE2L2CYP3A4SMN1; SMN2SLC9A1 | |
| SCHEMBL23674344 | 0.75 | SLC9A1 (0.61) | KEAP1NFE2L2CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL443877 | 0.73 | KHK (0.35) | TDP1 | |
| SCHEMBL4736844 | 0.73 | CA12 (0.46) | KEAP1CYP3A4SMN1; SMN2TSHRCASP1 | |
| SCHEMBL1317569 | 0.73 | ALDH1A1 (0.41) | KEAP1NFE2L2CYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088291-A1 | AROMATIC AMINE COMPOUND AND APPLICATION THEREOF | 武汉众诚康健生物医药科技有限公司 | 2023-05-25 | — | — | WO | disclosed |