Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711351 | 0.80 | GAA (0.52) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL20018349 | 0.76 | TSHR (0.55) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL13391946 | 0.75 | POLB (0.53) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL27727625 | 0.73 | TSHR (0.59) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL3496640 | 0.72 | ALDH1A1 (0.68) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL26468132 | 0.72 | TSHR (0.49) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL6179815 | 0.71 | MAPK1 (0.50) | TSHRKMT2AMAPTLMNANPC1 | |
| SCHEMBL16636997 | 0.70 | LMNA (0.50) | TSHRKMT2AALDH1A1POLBMAPT | |
| SCHEMBL4690902 | 0.70 | POLB (0.57) | KMT2AALDH1A1POLBMAPTGAA | |
| SCHEMBL269404 | 0.70 | KYNU (0.62) | ALDH1A1KYNUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023166172-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-09-07 | — | — | WO | disclosed |
| EP-3018123-B1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2023-05-10 | — | — | EP | disclosed |