Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25510170 | 0.89 | SIGMAR1 (0.46) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| SCHEMBL25515345 | 0.84 | TAAR1 (0.46) | SIGMAR1SLC6A4MAPTCYP2D6 | |
| SCHEMBL25509953 | 0.84 | TAAR1 (0.46) | SIGMAR1SLC6A4MAPTCYP2D6 | |
| SCHEMBL25515982 | 0.77 | SLC6A4 (0.42) | SIGMAR1SLC6A4HTR2AHTR2B | |
| SCHEMBL25510072 | 0.75 | SLC6A4 (0.37) | SLC6A4 | |
| SCHEMBL25510071 | 0.74 | HTR2A (0.36) | SLC6A4MAPTHTR2A | |
| SCHEMBL7169853 | 0.74 | ALDH1A1 (0.37) | MAPTTHRB | |
| SCHEMBL25510168 | 0.72 | TAAR1 (0.43) | SIGMAR1SLC6A4CYP2D6 | |
| SCHEMBL25175015 | 0.70 | — | — | |
| SCHEMBL25509947 | 0.70 | SIGMAR1 (0.54) | SIGMAR1SLC6A4LMNAMAPTADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |