Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25510171 | 0.88 | SLC6A4 (0.35) | HTR2ASLC6A4 | |
| SCHEMBL25515982 | 0.83 | SLC6A4 (0.42) | HTR2ASLC6A4 | |
| SCHEMBL25510072 | 0.78 | SLC6A4 (0.37) | SLC6A4 | |
| SCHEMBL7169853 | 0.76 | ALDH1A1 (0.37) | HTTATML3MBTL1KDM4ECHEK1 | |
| SCHEMBL25510070 | 0.74 | SIGMAR1 (0.49) | HTR2ASLC6A4MAPT | |
| SCHEMBL25515345 | 0.73 | TAAR1 (0.46) | SLC6A4KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL25509953 | 0.73 | TAAR1 (0.46) | SLC6A4KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL6949233 | 0.72 | KDM4E (0.37) | L3MBTL1KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL7073068 | 0.70 | TBXAS1 (0.44) | HTTATML3MBTL1KDM4ECHEK1 | |
| SCHEMBL25516018 | 0.70 | SLC6A2 (0.44) | HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |